

Principal Investigator
바이오융합공학과 김양희 교수
Yang-Hee Kim, Ph.D.
Education
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Ph.D. in Neuroscience, Seoul National University, Korea (1997~2000)
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M.S. in Cell Biology, Seoul National University, Korea (1993~1995)
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B.S. in Biology, Yonsei University, Korea (1988~1992)
Research and Professional Experience
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2020~present: Founder and CTO, Zincure Corp. (Faculty Startup)
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2016~Present: Professor in Dept. of Integrative Bioscience and Biotechnology, Sejong University
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2008~2015: Associate Professor in Dept. of Molecular Biology, Sejong University
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2009~2010: Visiting Professor in Sanford-Burnham Medical Research Institute, La Jolla, CA, USA
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2004~2008: Assistant Professor in Dept. of Molecular Biology, Sejong University
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2002~2004: Instructor in Dept. of Molecular Biology, Sejong University
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2000~2002: Postdoctoral Researcher, National Creative Research Initiative Center for the Study of CNS Zinc, University of Ulsan College of Medicine, Seoul, Korea

Zincure Researcher

선임 연구원 Senior Researcher
김기령 Ki-Ryeong Kim, Ph.D.
Education
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Ph.D. in Integrative Bioscience and Biotechnology, Sejong University, Korea (2013~2019)
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B.S. in Molecular biology, Sejong University, Korea (2006~2012)
Research Experience
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Postdoctoral researcher in Integrative Bioscience and Biotechnology, Sejong University (2020~2021)
Research Interests / Current Projects
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Development of therapeutics for neurodegenerative diseases
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Zinc-mediated lysosomal activation mechanisms
Publications
Patents
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Novel peptide and use thereof. KR20250009999A, WO2023229442A1, JP2025517813A, CN119403821A, EP4534546A1 (Filling Date: May 26, 2023)
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Novel peptide and use thereof. KR20250010000A, WO2023229445A1, JP2025519164A, CN119403819A, EP4534545A1 (Filling Date: May 26, 2023)

주임 연구원 Research Associate / Lab Manager
이현승 Hyun Seung Lee, M.S.
Education
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M.S. in Integrative Bioscience and Biotechnology, Sejong University in Korea (2020~2022)
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B.S. in Integrative Bioscience and Biotechnology, Sejong University in Korea (2015~2020)
Research Interests / Current Projects
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Development of therapeutics for ALS
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Investigation of zinc-centered pathogenic mechanism in ALS
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Research on the role of LMP in neurodegenerative diseases
Publications
Patents
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Novel peptide and use thereof. KR20250009999A, WO2023229442A1, JP2025517813A, CN119403821A, EP4534546A1 (Filling Date: May 26, 2023)
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Novel peptide and use thereof. KR20250010000A, WO2023229445A1, JP2025519164A, CN119403819A, EP4534545A1 (Filling Date: May 26, 2023)

연구원 Research Assistant
김동혁 Dong-hyuk Kim. M.S.
Education
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M.S. in Neuroscience, Sejong University, Korea (2022~2024)
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B.S. in Integrative Bioscience and Biotechnology, Sejong University, Korea (2016~2022)
Research Interests / Current Projects
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Development of Stroke therapeutics
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Investigation of MMP-9-mediated neuroinflammatory mechanisms
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Exploration of the therapeutic potential of MMP-9 inhibitor in CNS disorders
Patents
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New compounds and their uses. KR/20240080461 (Filling Date: Jun 20, 2024)
Graduate Students

박사과정 Ph.D program
이진연 Jin Yeon Lee
Education
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M.S. in Molecular Biology, Sejong University, Korea (2004-2006)
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B.S. in Molecular Biology, Sejong University, Korea (2000-2004)
Research Experience
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Principal Researcher, Research and Development Institute / BioSolution. o., Ltd. (2021-2022)
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Senior Researcher, Research and Development Institute / BioSolution. Co., Ltd. (2006-2019)
Research Interests / Current Projects
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Investigation of the role of zinc and lysosome in acute brain injury
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Elucidation of the zinc- and lysosome-dependent neuroprotective effects of Trehalose in ischemic brain injury
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Development of a novel MMP-9 inhibitor that prevents BBB breakdown in a pMCAO rat model
Publications
Patents
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New compounds and their uses. KR/20240080461 (Filling Date: Jun 20, 2024)
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Artificial cartilage containing chondrocytes obtained from costal cartilage and preparation process thereof. KR/10-0917422 (Registered: 2009.09.16)
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Preparation Method for therapeutic agent of bead-type chondrocyte. KR/10-1814440 (Registered: 2017.12.27)

석박통합과정 Integrated M.S.-Ph.D. Program
최한샘 Han-Saem Choi
Education
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B.S. in Integrative Bioscience and Biotechnology, Sejong University, Korea (2017~2021)
Research Interests / Current Projects
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Investigation of zinc’s essential role in progranulin-mediated lysosomal activation
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Elucidation of the protective effects of the lysosomal activator ZCS1 in progranulin-deficient transgenic mice
Publications

석사과정 M.S. Program
권예빈 Yeabin Kwon
Education
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B.S. in Integrative Bioscience and Biotechnology, Sejong University, Korea (2019~2024)
Research Interests / Current Projects
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Investigation of MMP-9-mediated neuronal death mechanisms in ischemic brain injury
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Development of novel MMP-9 inhibitor and exploration of therapeutic strategies for stroke
Publications

학석사연계과정 B.S.-M.S. Integrated Program thdgml04167@naver.com
김송희 Song-Hee Kim
Education
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B.S. in Integrative Bioscience and Biotechnology, Sejong University, Korea (2022~2025)
Research Interests / Current Projects
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Investigation of pathogenic factors contributing to ALS onset and the development of potential therapeutics
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Elucidation of pathological mechanisms underlying BMAA-induced neurotoxicity
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Evaluation of the protective effects and underlying mechanisms of the lysosomal activator ZCS1 in a BMAA-induced ALS-PD animal model
Undergraduate Students

학부생 Undergraduate Student
전관호 Kwanho Jeon
Education
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B.S. in Integrative Bioscience and Biotechnology, Sejong University, Korea (2019~present)
Research Interests / Current Projects
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Investigation of the pathological mechanisms of ALS
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Elucidation of the mechanism by which reduced RCAN1 and TRPML1 expression impairs TFEB activation and lysosomal biogenesis during BMAA-induced neurotoxicity